Holly finds two cowboys who are looking for work. The younger hand Jim looks up to Ben as the only father he has ever known as the two roam around looking for a place to settle. Ben isn't ready to settle down but Jim may have found a home.
Blinded after a fall, the Virginian strays to the home of a horse thief and his two sons, fired earlier from Shiloh.
In Arizona, Trampas is forced to work as foreman on a ranch staffed by men on probation from prison. The locals want them removed and the US Marshal in charge of the area is less than enthusiastic about them being there as well.
Clay discovers politics' unsavory side when he runs against an ambitious opponent for the territorial legislature.
Jim delivers the baby of a woman whose fugitive husband has run out on her, then cares for her and her property in addition to his responsibilities at the ranch.
A boy fleeing a reform school operator shelters at Shiloh Ranch while the Virginian and Trampas try to find his father.
Reporter/artist Julie Oakes arrives in Medicine Bow from Boston to do a story on the west. She falls in love with The Virginian but her interest in another man upsets him and results in problems due to her complicated past in Boston.
Trampas leaves on vacation but his plans go astray when he is picked up by a bounty hunter for murdering a popular doctor. He has to contend with a hostile town, planted evidence, and a saloon girl who swears she saw him commit the murder.
After being whipped, an Army private deserts the post commanded by his father and is found unconscious and injured on Shiloh property.
An aging sheriff arrives to visit old friend the Virginian, then invites him on a hunting trip that is actually a cover for tracking the last of a desperate band of bank robbers.
A pigtailed brat returns home from finishing school for a two week vacation as a beautiful woman catching Trampas' eyes again. They fall in love as she remembers the good times but her father wants her to return to school in the East.
An emergency recalls The Virginian so he allows Jim Horn to go alone with $4000 to complete a purchase of horses. Everyone takes Jim for a wet behind the ears youngster including the woman and her partner who steal the money he carries.
A long time captive of an Indian tribe returns to the husband who deserted her during an Indian raid, only to find her desire for revenge could destroy her daughter's wedding.
Trampas decides to track down where Cobey Jade obtained a silver watch that belonged to a friend. While with Jade who lives in an abandoned mining town, they are taken captive by a band of roving outlaws who believes Jade found gold there.
A stagecoach robbery interferes with the plans of a Southern belle who is traveling to Clearwater to marry her childhood sweetheart.
A newly married woman faces many problems, including a murder charge, after her husband's injury sets off a bid for power in his company.
An eastern combine wants to take over the Wyoming cattle market with Shiloh in the middle of their sights. A burned Shiloh and delayed cattle drive leads to a loss on the sale of cattle resulting in all the Shiloh hands being laid off.
Clay, Elizabeth, and Jim along with a small number of other passengers ride the train from Cheyenne to Medicine Bow. During the trip they get to know each other only to learn one is hiding a past that causes the train to be stopped.
A family takes over Shiloh at gunpoint, then lures the Graingers' friend, a Congressional candidate, to the ranch for revenge.
Jim's life is endangered after an Indian running from authorities hides out with the Shiloh wranglers on a cattle drive.
Clay is kidnapped by three gang members for a $20,000 ransom or the threat of his death and the burning of Medicine Bow. Adding to the situation is the wife of the gang leader staying at Shiloh in order to escape him but he wants her back.
Clay awaits a showdown with a young gunslinger, hired as a Shiloh ranch hand, who blames his father's death 20 years earlier on Grainger and refuses to listen to any explanation.
Poor Harve Yost turns into rich Harve when he finds a dying man with a saddle bag full of money and gets a $10,000 reward. Never a man to manage money or time, The Virginian advises him to buy a ranch but Harve tries to rival Shiloh.
A wounded bank robber hides his loot and dies in a saloon girl's room, making her the target of his partner.
