David Eigenberg
as Firefighter Christopher Herrmann
Joe Miñoso
as Firefighter Joe Cruz
Christian Stolte
as Lieutenant Randy "Mouch" McHolland
Taylor Kinney
as Captain Kelly Severide
Eamonn Walker
as Deputy Commissioner Wallace Boden
Jesse Spencer
as Captain Matthew Casey
Miranda Rae Mayo
as Lieutenant Stella Kidd
Kara Killmer
as Paramedic Sylvie Brett
Yuri Sardarov
as Firefighter Brian "Otis" Zvonecek
Monica Raymund
as Firefighter/Paramedic Gabriela Dawson
Daniel Kyri
as Firefighter Darren Ritter
Hanako Greensmith
as Paramedic Violet Mikami
Alberto Rosende
as Firefighter Blake Gallo
Charlie Barnett
as Firefighter/Paramedic Peter Mills
Jake Lockett
as Firefighter Sam Carver
Lauren German
as Paramedic Leslie Shay
Jocelyn Hudon
as Paramedic Lyla "Lizzy" Novak
Annie Ilonzeh
as Paramedic Emily Foster
Dermot Mulroney
as Battalion Chief Dom Pascal
Steven R. McQueen
as Paramedic Jimmy Borrelli
Brandon Larracuente
as Firefighter Sal Vasquez
Dora Madison Burge
as Paramedic Jessica "Chili" Chilton
Teri Reeves
as Dr. Hallie Thomas
Adriyan Rae
as Paramedic Gianna Mackey
Da'Vinchi
as Firefighter Candidate Marcus Burke