Melinda Gordon has always had the ability to see and talk to dead people. These earth bound spirits, the ones who have yet to cross over to the other side, seek Melinda's help in communicating with the living and resolving unfinished business.
Melinda helps a boy reassure his mother that his death was not her fault, while also preventing the boy's father from seeking revenge on the man who sold them the broken down car that took part in his death.
When a teenage psychiatric patient, Natalie, escapes, her rebellious ghost twin asks Melinda for help, claiming Natalie doesn't belong in the clinic. Their parents placed her there for believing she can still feel Zoë's presence.
Melinda agrees to help a deceased fiancé communicate with his grieving fiancé and find the man who received his heart donation, in an effort to bring closure so they can both move on.
When Melinda and Andrea are hired to auction off furniture from an inn that was recently sold, Melinda encounters the mischievous ghosts of three young boys who refuse to leave the inn.
A year after a teenage boy, Jason Shields, dies in a freak accident after discovering he was adopted, Melinda must help him find his birth mother before he can crossover.
When a young woman dies following a routine procedure in the operating room, Melinda uncovers the truth that the doctor is secretly suffering from dementia and made a mistake during the women's operation that caused her death.
When Jim starts behaving uncharacteristically, Melinda learns Jim is being haunted by the ghost of an ex-con, Julian Borgia, who has been attached to Jim ever since Jim was unable to save Julian's life in route to the hospital.
Soon after Melinda's car is stolen by a troubled teenage boy, Kirk Jensen, Kirk's dead mother, Lacy, sends Melinda messages through Electronic Voice Phenomena (EVP)or "white noise" in her car radio and other electronics.
A young bride-to-be is haunted by the dead wife, Ursula, of her fiancé before their upcoming wedding. Melinda learns Ursula died in a car crash on the way to her wedding reception with Mark, and now she can't bear to see Mark marry someone else.
When an up and coming boxing sensation is haunted by the ghost of his mother, whose death caused a rift between him and his father, Melinda must broker peace between them before the mother can crossover.
While Andrea prepares to do standup at a nearby comedy club that is closing its doors, Melinda encounters a troubled dead stand-up comedian (Marty Golden), who is haunting the old comedy club, along with other dead comics.
Melinda's mysterious new neighbor is haunted by an old classmate's dead grandfather, who suspects Tom kidnapped and killed his granddaughter.
The ghost of an executed prisoner seeks Melinda's help in uncovering a contract for his valuable paintings before they're sold and his estranged daughter and struggling artist doesn't see a penny of what the contract says she is entitled to.
When Melinda's first ghost reappears, her presence triggers Melinda to remember when she first discovered her "gift" and the strain it put on her relationship with her mother, who couldn't understand what Melinda was going through.
When the ghost of Andrea's friend starts haunting her, Andrea learns that he was hospitalized in a hiking accident and every time he flat lines, his ghost tries to give clues to the location of his brother, who went missing during their hike.
When Melinda and Andrea help a workaholic fashion designer, Christine, auction her belongings, Melinda discovers Christine and her baby daughter's nanny are being haunted by the malicious ghost of Christine's son, Daniel.
When a traveling carnival comes to Grandview, Melinda encounters the revengeful ghost of a magician (Edward), who thinks his death during an underwater escape stunt wasn't an accident.
The ghost of an African American man attacked and killed during a fight with a white co-worker in the 1970's, haunts the former prosecutor turned judge who didn't file charges against the white co-worker even though he had good reason to.
When Melinda falls and injures her head, she wakes up to a world without ghosts and fears she has lost her "gift".
When the heat goes out at Melinda's house and shop, and Melinda gets strange visits from a flight attendant ghost who complains of being cold, Melinda welcomes the ability to help a ghost again but can't make sense of the messages she is being sent.
Following the jetliner crash just outside of Grandview, Melinda tries to get the confused ghost passengers to crossover, but she encounters an evil spirit who is working against her to keep the ghosts earthbound for "work" he has to do.
