Billy Connolly
as Billy MacGregor
William G. Schilling
as Dr. Harold Samuels
Jeannetta Arnette
as Bernadette Meara
Leslie Bega
as Maria Borges
Dan Frischman
as Arvid Engen
Robin Givens
as Darlene Merriman
Khrystyne Haje
as Simone Foster
Jory Husain
as Jawaharlal Choudhury
Tony O'Dell
as Alan Pinkard
Brian Robbins
as Eric Mardian
Kimberly Russell
as Sarah Nevins
Dan Schneider
as Dennis Blunden
Tannis Vallely
as Janice Lazarotto
Michael DeLorenzo
as Alex Torres
Lara Piper
as Viki Amory
Rain Pryor
as Theola June "T.J." Jones
Ke Huy Quan
as Jasper Kwong
De'voreaux White
as Aristotle McKenzie
Howard Hesseman
as Charlie Moore