Michael Imperioli
as Detective Mike Sellitto
Russell Hornsby
as Lincoln Rhyme
Arielle Kebbel
as Amelia Grace Sachs
Roslyn Ruff
as Claire
Ramses Jimenez
as Eric Castillo
Brooke Lyons
as Kate
Tate Ellington
as Felix
Brían F. O'Byrne
as The Bone Collector
Courtney Grosbeck
as Rachel Sachs