Brenda Blethyn
as DCI Vera Stanhope
Jon Morrison
as DC Kenny Lockhart
Riley Jones
as DC Mark Edwards
Kenny Doughty
as DS Aiden Healy
Ibinabo Jack
as DC Jacqueline "Jac" Williams
David Leon
as DI Joe Ashworth
Kingsley Ben-Adir
as Dr. Marcus Summer
Paul Kaye
as Dr. Malcolm Donahue
Paul Ritter
as Forensic Pathologist Billy Cartwright
Sarah Kameela Impey
as Dr. Paula Bennett
Sonya Cassidy
as Celine Ashworth
Cush Jumbo
as DC Bethany Whelan
Clare Calbraith
as DC Rebecca "Shep" Shepherd
Noof Ousellam
as DC Hicham Cherradi
Wunmi Mosaku
as DC Holly Lawson
Rhiannon Clements
as DC Steph Duncan
Christopher Colquhoun
as Dr. Anthony Carmichael