Winona Ryder
as Joyce Byers
Caleb McLaughlin
as Lucas Sinclair
Finn Wolfhard
as Mike Wheeler
Gaten Matarazzo
as Dustin Henderson
Natalia Dyer
as Nancy Wheeler
David Harbour
as Chief Jim Hopper
Joe Keery
as Steve Harrington
Charlie Heaton
as Jonathan Byers
Millie Bobby Brown
as Jane "Eleven" Hopper
Noah Schnapp
as Will Byers
Cara Buono
as Karen Wheeler
Sadie Sink
as Maxine "Max" Mayfield
Nell Fisher
as Holly Wheeler
Maya Hawke
as Robin Buckley
Brett Gelman
as Murray Bauman
Priah Ferguson
as Erica Sinclair
Dacre Montgomery
as Billy Hargrove
Jamie Campbell Bower
as Henry Creel / Vecna
Matthew Modine
as Dr. Martin Brenner
Paul Reiser
as Dr. Sam Owens
Linda Hamilton
as Dr. Kay
Sean Astin
as Bob Newby