Alex O'Loughlin
as Steven McGarrett
Scott Caan
as Danny "Danno" Williams
Daniel Dae Kim
as Chin Ho Kelly
Grace Park
as Kono Kalakaua
Chi McBride
as Lou Grover
Taylor Wily
as Kamekona
Dennis Chun
as Sergeant Duke Lukela
Masi Oka
as Dr. Max Bergman
Jorge Garcia
as Jerry Ortega
Ian Anthony Dale
as Adam Noshimuri
Meaghan Rath
as Tani Rey
Beulah Koale
as Junior Reigns
Michelle Borth
as Catherine Rollins
Kimee Balmilero
as Dr. Noelani Cunha
Lauren German
as Lori Weston
Katrina Law
as Quinn Liu