Matt Czuchry
as Dr. Conrad Hawkins
Manish Dayal
as Dr. Devon Pravesh
Bruce Greenwood
as Dr. Randolph Bell
Malcolm-Jamal Warner
as Dr. AJ Austin
Emily VanCamp
as Nicolette "Nic" Nevin
Jane Leeves
as Dr. Kitt Voss
Shaunette Renée Wilson
as Dr. Mina Okafor
Jessica Lucas
as Billie Sutton
Anuja Joshi
as Leela Devi
Glenn Morshower
as Marshall Winthrop
Morris Chestnut
as Dr. Barrett Cain
Kaley Ronayne
as Dr. Kincaid "Cade" Sullivan
Melina Kanakaredes
as Dr. Lane Hunter
Andrew McCarthy
as Dr. Ian Sullivan
Miles Fowler
as Trevor Daniels
Merrin Dungey
as Claire Thorpe
Moran Atias
as Renata Morali