In the series pilot, Euan invites Mike's girlfriend, Liz, to move in with them---a proposition that makes Mike nervous. To retaliate, Mike invites two of Euan's gal pals to their housewarming party.
When Mike and then Liz contract a certain sexually transmitted condition, Mike blames the assumed originator---Euan. The irritating malady hampers both Mike and Liz's anniversary dinner and Euan's date with a friend from college.
Liz finds out about Mike's stash of adult videos and is surprisingly okay with it---so okay that she offers to watch some with him. But the sexy adventure in cinema turns out to be a bit of a let-down for Mike. Euan, meanwhile, endeavors to impress his incredibly jaded girlfriend (Tammie Vanderpool).
On a night out with Chau and Euan, Mike repeatedly rejects women in favor of being faithful to Liz---who ends up kissing an old flame during the same evening. Also, Chau gets angry at Euan for constantly stealing prospective dates.
Euan's quest to find a steady girlfriend lands him Ginger (Kristen Miller)---an artist who Mike believes is taking Euan for all he's worth. Meanwhile, Liz proves to Mike that her revealing clothing makes him uncomfortable.
When Liz and her wild, flirty friend (Perrey Reeves) stay at the apartment for the weekend, Mike hopes for a ménage à trois. Euan, who has resolved to remain celibate with his current girlfriend, serves as Mike's mentor. Angelica: Sarah Shahi.
Mike's strange parents (Stephen Tobolowsky, Mary Gross) visit, allowing Mike to finally bond with his erstwhile, emotionally distant father. Unfortunately, Euan finds Mr. Platt in a compromising position with another woman.
Finding it difficult to keep up with the incredibly successful Euan, Mike tries to solve his money woes by taking on a second job at Chau's restaurant. Euan offers to help, but Mike refuses any more financial aid from his roommate.
After a co-worker spreads a rumor that he's gay, Euan is troubled upon learning that people don't have a hard time believing it. Mike, meanwhile, is overjoyed upon meeting Liz's unexpectedly unimpressive ex-boyfriend (Matt Price).
After Mike learns of Liz's wild past, he decides to make up for lost time by doing the crazy things he missed out on when he was younger.
In dire need of a job he actually enjoys, Mike seeks advice from a decidedly unreliable career counselor (Jason Biggs). Euan, meanwhile, concentrates his efforts on trying to win over their new neighbor, a B-movie actress (Jessica Collins).
Mike's increasing comfort level with Liz leads him to engage in behavior she doesn't entirely welcome. Meanwhile, Euan resolves to avoid a woman (Whitney Dylan) who routinely shows up in his life to break his heart; and Status Quo works on new song lyrics with Chau.
Sick of living with Euan, Mike decides to stay at Lauren's for a while. As revenge, Euan invites Chau to live in Mike's room. The unlikely duo get along well, until Chau's behavior gets out of hand.
After Mike and Euan say that his "posse" is a bunch of yes-men, Status Quo fires them and invites his neighbors to hang with him. Unfortunately, he treats Euan more like a slave than a friend. Dustin Diamond ("Saved by the Bell") has a cameo.
In order to get women to notice them more, Chau and Euan pretend to be in a rock band; Mike irks Liz when he drunkenly proposes marriage and then forgets all about it.
Mike and Chau start going to a gym where a lot of nude men hang out; Euan dates Liz's hearing-impaired friend (Shoshannah Stern), who turns out to be less friendly than anyone realizes.
Mike tells Euan to stay away from an attractive visiting friend (Jenna Fischer), explaining that she is his "backup girl," should things not work out with Liz. Meanwhile, Chau pulls out all the stops to try to win a contest for a big-screen TV.
Liz sets Chau up with her equally bizarre roommate, creating a romance more ridiculous than anyone could have imagined. Meanwhile, Euan lies about his age in order to date 45-year-old woman (Tanya Roberts).
Chau's new girlfriend (Shannon Elizabeth) is a hazard to his health---she keeps getting him beaten up by strangers. Meanwhile, irresponsible dog-sitters Mike, Euan and Liz watch Status Quo's treasured canine.
Increasingly self-conscious about his natural look, Euan goes to see an eccentric urologist (Eugene Levy) about a circumcision. Meanwhile, Mike spruces up his appearance for Liz.
Euan looks for a way out of the limelight when he gets trapped in a relationship with a roomie from MTV's "The Real World." Meanwhile, Mike gets a job on the set of an adult film; and Liz and Status Quo start hanging out together.
