Jane Seymour
as Dr. Michaela "Mike" Quinn
Shawn Toovey
as Brian Cooper
Chad Allen
as Matthew Cooper
Joe Lando
as Byron Sully
Orson Bean
as Loren Bray
Jim Knobeloch
as Jake Slicker
Erika Flores
as Colleen Cooper
Jessica Bowman
as Colleen Cooper
Frank Collison
as Horace Bing
William Shockley
as Hank Lawson
Geoffrey Lower
as Rev. Timothy Johnson
Henry G. Sanders
as Robert E
Jonelle Allen
as Grace
Barbara Babcock
as Dorothy Jennings
Helene Udy
as Myra Bing
Larry Sellers
as Cloud Dancing
Jason Leland Adams
as Preston A. Lodge III
Brandon Douglas
as Dr. Andrew Cook
Gail Strickland
as Olive Davis